Mycoplasma pulmonis

Genes

microbe: DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF PYRUVATE COMPLEX).
human protein: DLD: dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex)

The NCBI states that the molecule is a component in the "pyruvate complex." After searching the web, I found that the pyruvate complex basically reduces NAD+ to NADH, which then drives "oxidative phosphorylation," which is responsible for producing ATP (the molecule primarily responsible for available energy in the cell)

Alignment

 
Score =  189 bits (479), Expect = 4e-48 
 Identities = 138/468 (29%), Positives = 233/468 (49%), Gaps = 25/468 
(5%) 
 
Best Alignment: 
 
Query: 5   DFVIIGSGPGGYSLALILSKLG-KKVAIAERKNFGGSCINEGCVPTKGLVKVARTYELIK 63 
           D  +IGSGPGGY  A+  ++LG K V I + +  GG+C+N GC+P+K L+  +  Y +   
Sbjct: 43  DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH 102 
 
Query: 64  NS--SKFGIKVNDFSFDWKQIIKRKNEIKDTLNNSIEKNLELNNVKIFKAEAKVLKDKSI 121 
            +  +  GI++++   +  +++++K+     L   I    + N V       K+     + 
Sbjct: 103 GTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQV 162 
 
Query: 122 EVNNTK-----IYAEKIIIATGSRARKISFDGSDKALEKQVLVDSNYLLDMQEVPKSIAF 176 
                      I  + I+IATGS      F G    +++  +V S   L +++VP+ +   
Sbjct: 163 TATKADGGTQVIDTKNILIATGSEVTP--FPGI--TIDEDTIVSSTGALSLKKVPEKMVV 218 
 
Query: 177 IGAGPISLELGYVLSALGSDVTLLEGRDQILA-NFDHDVREEVLKYLEQKNIKYFTSTKV 235 
           IGAG I +ELG V   LG+DVT +E    +     D ++ +   + L+++  K+  +TKV 
Sbjct: 219 IGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKV 278 
 
Query: 236 LKYDQ--DG-----LHFSVGEKNKVINPEKIALSVGREANLE--AVEDLDLELNPNKTIK 286 
               +  DG     +  + G K +VI  + + + +GR    +   +E+L +EL+P   I  
Sbjct: 279 TGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIP 338 
 
Query: 287 VDDKLETSIKGIYALGDVTGKMMLSTIAYKHGDVIVNNLINNKEVKLDYKKVPHTIYLSP 346 
           V+ + +T I  IYA+GDV    ML+  A   G + V  +     V +DY  VP  IY  P 
Sbjct: 339 VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGA-VHIDYNCVPSVIYTHP 397 
 
Query: 347 EISSIGLSEEEAKKTYGENLLAIKIPSERLPRNHADGNLGYGFFKLIINKDTKQVLGASI 406 
           E++ +G SEE+ K+  G      K P     R   + +   G  K++  K T +VLGA I 
Sbjct: 398 EVAWVGKSEEQLKEE-GIEYKVGKFPFAANSRAKTNADTD-GMVKILGQKSTDRVLGAHI 455 
 
Query: 407 ILENSSLIINEISIAMNNDLTIYDLAKSPHVHPTLAEALYYAIRDLSF 454 
           +   +  ++NE ++A+    +  D+A+  H HPTL+EA   A    SF 
Sbjct: 456 LGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASF 503