Aeropyrum pernix K1

Genes

gi = 5103431 - long hypothetical multiple sugar-binding transport ATP-binding protein [Aeropyrum pernix]
gi = 7445558 - probable ATP-binding cassette transporter ABC-3 - human

The both proteins are binding to ATP (the main energy carrier in cells). Structural similarity implies functional.

Alignment


Identities = 66/217 (30%), Positives = 113/217 (52%), Gaps = 13/217 (5%)

Query: 31  AVDHVDLSIKDGEFFVLLGPSGCGKTTTLRLIAGLEYPDEGRILIDGEDVTFKDPKDRNV 90
           AV  ++L++ +G+  VLLG +G GKTTTL ++ GL  P  GR  I G +++      +++
Sbjct: 548 AVRDLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEIS------QDM 601

Query: 91  AMVFQNYALYP-HMSVFDNIAFTLHL--RRKEMGLTKDDIRRRVIEVAKLLRIEDLLDRK 147
             + ++  L P H  +FDN+    HL    +  GL++      V ++  ++ +ED  + +
Sbjct: 602 VQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSR 661

Query: 148 PGQLSGGXXXXXXXXXXXXXXPKVWLMDEPLSNLDALLRLAMRAELKKLQKDLKITTVYV 207
              LSGG               KV ++DEP S +DA+ R A+   L++ + D   T V  
Sbjct: 662 SRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKSDR--TIVLT 719

Query: 208 THDQAEAMSMADRIAVMNKGRVVQVGTPEEVYMRPKH 244
           TH   EA  + DRIA+M KG +   G+   ++++ K+
Sbjct: 720 THFMDEADLLGDRIAIMAKGELQCCGS--SLFLKQKY 754