----------------------------------------------------------------------------
DATA Set 2: COG0532
----------------------------------------------------------------------------
Organism: Caulobacter crescentus CB15
Description: translation initiation factor IF-2
PID: 16124298
Length of upstream non-coding sequence: 195
Label: CC0042
Organism: Rickettsia prowazekii
Description: TRANSLATION INITIATION FACTOR IF-2 (infB)
PID: 15604407
Length of upstream non-coding sequence: 214
Label: RP552
Organism: Synechocystis sp. PCC 6803
Description: initiation factor IF-2
PID: 16329288
Length of upstream non-coding sequence: 578
Label: slr0744
Organism: Mycobacterium leprae
Description: initiation factor IF-2
PID: 15827818
Length of upstream non-coding sequence: 65
Label: ML1556
Organism: Mycobacterium tuberculosis H37Rv
DEFINITION infB
PID: 15609976
Length of upstream non-coding sequence: 86
Label: Rv2839c
CC0042 --------------MEVRPGPFLTWNERFFSRVPPGGSTSERMSDENENGRPGGRTPMTL
RP552 ------------------------------------------MTDNQE-----------I
slr0744 MNNAKVRIYDLSKELNLENRDILDICERLNVAAKSHSSTISESDAERIKAAAEKFTPQQP
ML1556 ------------------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAP
Rv2839c -----------------MAAGKARVHELAKELGVTSKEVLARLSEQGEFVKSASSTVEAP
:
CC0042 KPRQGSVSAGVVKQSFSHGRTKTVVVETKRTRTHAPASGNLAAPSSAERRHGEAPAPRPA
RP552 KPKK-----------LTLGNSKLLLNKSFDSLTGAQSFVNAKSKTLVEVRK---------
slr0744 KKPRVASRPESKEDKSDPKQQKILAIHHKQEKSGGPSPARPTPPPRPKLQAPKAPTPPQP
ML1556 VARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQ
Rv2839c VARRLRESFGGSKPAPAKGTAKSPGKGPDK----SLDKALDAAID-MAAGNGKATAAPAK
: : . .
CC0042 PPQGGGGGSAGGLSQEELRARQRVVDAAREAQARQVAEQAAAEARARAAQEAAQREAAAK
RP552 --SSIGSTTTISLNKERNSLDQSVIDSNKE--------------------EFNRRLSILK
slr0744 PVAKASAPKIQKQEEPAQEAPKSVAPPTQPLAPPPVPSLQSPPS------KPAPPTPPAK
ML1556 VDHSAAVVPIVAGEGPSTAHREELAPPAGQPS------------------EQPGVPLPGQ
Rv2839c AADSGGAA-IVSPTTPAAPEPPTAVPP---------------------------------
. .
CC0042 AAAERAAAAPPPVAQAPAAPAPAAPVTPPPAAPQAPRPVAQAPVAPSAPRQDAPRQDTRA
RP552 KAAEQSKLHDP---------AQISTLSKLASINQSINSKNEQSITDKAVEQKHQNIE---
slr0744 KAAPAPRLAGPPGRTASPNKTAVPAPAKPKVNRPEIVSLKDNRGQARSPGDREEKVAIAA
ML1556 QGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRP----
Rv2839c --SPQAPHP---GMAPGARPGPVPKPGIRTPRVGNNPFSSAQPADRPIPRPPAPRPGTAR
: . . .
CC0042 AAPGQTRTYEPSRDRRDDRPSTTTYRPAPQGDRPFNQRAPRPDANANFGQRAPRPEGDRP
RP552 -------------------------------DNKVEIAAKIVQDNENISSQIPKKKKE--
slr0744 PEPPKPK------------------------VELRRPKPPRPEEDENLPELLEFPPLSRG
ML1556 ---------------------------------SASPSSMSPRPGGAVGGGGPRPPRT--
Rv2839c PGVPR---------------------------PGASPGSMPPRPGGAVGG--ARPPRP--
. . .
CC0042 RGPRPDGDRPQGDRGGYRGDRPQGDRPQGDRPQQTVRYSALAPRPAPGARGPGGPPRGPR
RP552 ---------------------------------------TLAKSVLVGMR--------TR
slr0744 KGVDGDNDADDGD--------------------------LLSTEKPKPKLKRPTPPRLGK
ML1556 -------------------------------------------GVPRPGGGRPGAPVGGR
Rv2839c -------------------------------------------GAPRPGG-RPGAPGAGR
:
CC0042 PGVPAAAPATPEIQRATRSAPRPGGGAMDRRPDEDDDRRKNAAPNKAVSRVKGAPQRREG
RP552 YGIEEEP-------------------ALEKTVDN-----KVVVPKIKLEESK----KFKK
slr0744 PDQWEDDEDEKANKAKAANKGKRRPKMDDDDDDLDIDGDNGPKPTLVSLSIARPPKPKSL
ML1556 SDAGGGN---------------YRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGA
Rv2839c SDAGGGN---------------YRGGGVGAAPGTG---FRGRPGGG---GGGRPGQRGGA
. . .
CC0042 RLTIQAVAGDGDSADRMRSLASVRRAREREKEKRRGGAVEQARVAREVVIPDVITVQELS
RP552 ADLFNMLSDDENGSGRTRSLASIKRARE--KEKRKLVSQVPEKVYREVTIPEVIGVGDLA
slr0744 AAKPSTPTVAKVKKPTLKSEAGSSAGGSSRSRGDRRDRKEVVQKPEVIMLDRSLTVRDLA
ML1556 AGAFGRPGGAPRRGR--KSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFA
Rv2839c AGAFGRPGGAPRRGR--KSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFA
:* . . . : : : :::
CC0042 NRMAVRGVDIIKFLMRQGVMLKINDVIDNDTAELVATEFGHTVKRVS--EADVEEGFIGA
RP552 NAMSERVADVIKELMKLGILANASQTIDADTAELVATNLGHTVTRVQ--ESDVEN-ILIN
slr0744 DLLKISETDIIKRLFLKGVAVQITQTLDEETARMVAESFEVAVETPERVAAAAKTTEMLD
ML1556 EKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFD
Rv2839c DKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLESFD
: : . ::: *: * .: :. :* .::. .: * . :
CC0042 DDH------DEHMDLRPPVVTIMGHVDHGKTSLLDALRSTDVAAGEAGGITQHIGAYQVR
RP552 DDK------VEDLRTRAPVVTVMGHVDHGKTSLLDALKSTDIAAGELGGITQHIGAYRVT
slr0744 EAD------LDNLVRRPPVVTIMGHVDHGKTTLLDSIRKTKVAQGEAGGITQHIGAYHVE
ML1556 LTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVG
Rv2839c LSYGEDEGGEEDLQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVA
:.: *.****:********* ***:::.:.: .* **********:*
CC0042 LKD---GQRVTFLDTPGHAAFSSMRARGANITDIVVLVVAGDDGVMPQTIEAIKHAKAAE
RP552 LAD---SKAITFIDTPGHEAFSEMRSRGAKVTDIVIIVVAADDGIKTQTVEAINHAKAAG
slr0744 VEHNDKTEQIVFLDTPGHEAFTAMRARGAKVTDIAILVVAADDGVQPQTKEAISHAKAAG
ML1556 VDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAAD
Rv2839c VDLDGSQRLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAAD
: . :.*:***** **: **:***: ***.::***.***: .** ***.**:**
CC0042 VPIIVAVNKMDKPGSDPTRVVNELLQHEIVVESLGGDTQLIEVSAKARTGLDNLLEAILL
RP552 VPIIVAINKIDKPDIDIERIKNELYVHEIIGEEAGGDVIFIPISALKKINLDKLEEAILL
slr0744 VPLIVAINKVDKPEANPDRIKQELSELGLLAEEWGGDTIMVPVSALNGDNLDGLLEMILL
ML1556 VPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLL
Rv2839c VPIVVAVNKIDKEGADPAKIRGQLTEYGLVPEEFGGDTMFVDISAKQGTNIEALEEAVLL
**::**:**:** : :: :* :: *. ***. :: :** .:: * * :**
CC0042 QA-EVLDLKANPDRSADGVVIEAKLDKGRGAVSTVLVNRGTLKRGDIVVAGSQWGKVRAL
RP552 IS-EMQDLKASPFGLASGVVIESKIEKGRGTLTTILVQRGTLRNGDIIIAGTSYGKVKKM
slr0744 VS-EVEELVANPNRQAKGTVIEANLDRTRGPVATLLIQNGTLRVGDAIVVGAVYGKIRAM
ML1556 TADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRM
Rv2839c TADAALDLRANPDMEAQGVAIEAHLDRGRGPVATVLVQRGTLRVGDSVVAGDAYGRVRRM
: :* *.. *.*..**::::: **.::*:*::.***: ** ::.* :*::: :
CC0042 LNERNEQLQEAGPATPVEILGLDGVPSPGDAFAVVENEARARELTEYRIRLKREKSMAPV
RP552 INDKGREILEATPSVPVEIQGLNEVPFAGDQFNVVQNEKQAKDIAEYRIRLAKEKKIS-V
slr0744 IDDRGDKVEEASPSFAVEILGLGDVPAAGDEFEVFTNEKDARLQAEARAMEDRQTRLQQA
ML1556 VDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARS
Rv2839c VDEHGEDVEVALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARS
::::. .: * *: .*:: *: ** .** * *. :: *: :: * ::
CC0042 GAGASMADMMAKLQ--DKKLKELPLVIKADVQGSAEAIIGSLDKMATD-EVRARIILSGA
RP552 ASRSSLEELLLKASG-NSKIKELPLIIKCDVQGSIEAISGSLLKLPSD-EIKLRILHSGV
slr0744 MSSRKVTLSSISAQAQEGELKELNIILKADVQGSLGAILGSLEQLPQG-EVQIRVLLASP
ML1556 RKRISLEDLDSALK----ETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGV
Rv2839c RKRISLEDLDSALK----ETSQLNLILKGDNAGTVEALEEALMGIQVDDEVVLRVIDRGV
.: . : .:* :::* * *: *: :* : . *: *:: .
CC0042 GAISESDVMLAKGAGAPVIGFNVRASAQARALAEREGVEIRYYAIIYDLLDDIKGVLSGM
RP552 GPITESDVSLAHVSSAIVVGFNVRAWANALTAAEKTKVDIRYYSIIYNLIDDVKAIMSGM
slr0744 GEVTETDVDLAAASGAIIIGFNTTLASGARQAADQEGVDIREYDIIYKLLDDIQGAMEGL
ML1556 GGITETNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGM
Rv2839c GGITETNVNLASASDAVIIGFNVRAEGKATELASREGVEIRYYSVIYQAIDEIEQALRGL
* ::*::* ** :.* ::***. . * *.: *:** * :**. :*::: : *:
CC0042 LAPIQRETFLGNAEVLQAFDISKIGKVAGCKVTEGVVRKGAKVRIIRQDIVVLELGTLQT
RP552 LEPIVREQYIGSVEIRQIFNITKIGKIAGSYVTKGIIKKGAGVRLLR-DNVVIHAGKLKT
slr0744 LDPEEIESSLGTAEVRAVFPVGRG-NIAGCYVQSGKIIRNRNLRVRRGDQVLFEG-NIDS
ML1556 LKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTS
Rv2839c LKPIYEENQLGRAEIRALFRSSKVGLIAGCLVTSGVMRRNAKARLLRDNIVVAENLSIAS
* * * :* .*: * : :**. : .* : :. *: * : *: . .: :
CC0042 LKRFKDEVNEVPVGQECGMMFAGFQDIKVGDTIECFTVEEIKRQLD-
RP552 LKRFKDEVKEVREGYECGIAFENYEDIREGDTVEVFELVQEQRQL--
slr0744 LKRIKEDVREVNAGYECGIGCSKFNDWKEGDIIEAYEMTMKRRTLAT
ML1556 LRREKDDVTEVREGFECGMTLG-YSDIKEGDVIESYELVEKQRA---
Rv2839c LRREKDDVTEVRDGFECGLTLG-YADIKEGDVIESYELVQKERA---
*:* *::* ** * ***: : * : ** :* : : .*