Grand Challenge 7
How do we advance new computational tools to unlock the mysteries of the brain?
Recent technological advances enable us to measure, model, and manipulate neural activity in living brains with unprecedented precision and scale. These capabilities promise to reveal the distributed brain-wide neural computations that underlie cognition, flexible behavior, and biological intelligence.
Allen School researchers are developing innovative theory, modeling, and machine learning techniques to realize this vision, including new computational theories of brain function, computational tools for complex data analysis and experimental design, and AI-enabled brain co-processors for next-generation brain-computer interfaces. This research could open up new avenues for diagnosing and treating neurological and psychiatric conditions that affect millions of people in Washington state and billions of people worldwide. And as technologies for neural data collection and neural interfaces become more powerful, we’re committed to ensuring they are developed and deployed in ways that are secure, privacy-preserving, fair and broadly accessible.
Selected Projects
Nature 2026 (to appear)
arXiv 2025
International Conference on Machine Learning (ICML), 2025.
Journal of Neural Engineering, 2025
Journal of Neural Engineering, 2025
IEEE Engineering in Medicine and Biology, 2025
arXiv preprint arXiv:2512.22568, 2025
Advances in Neural Information Processing Systems (NeurIPS), 2025
Conference on Computer Vision and Pattern Recognition (CVPR), 2025
arXiv, 2025
arXiv, 2025
Advances in Neural Information Processing Systems (NeurIPS), 2024
Advances in Neural Information Processing (NeurIPS), 2024
PLOS Computational Biology, 2024
Uncertainty in Artificial Intelligence (UAI), 2024
Advances in Neural Information Processing Systems (NeurIPS), 2024
Advances in Neural Information Processing Systems, 2024
Advances in Neural Information Processing Systems, 2024
Nature Medicine, 2024
Neural Computation, 2023
Journal of Neural Engineering, 2023
Nature Machine Intelligence, 2023
Advances in Neural Information Processing Systems (NeurIPS), 2023
Advances in Neural Information Processing Systems 36 (NeurIPS 2023)
Advances in Neural Information Processing Systems (NeurIPS), 2022
Journal of Neural Engineering, 2021
International Conference on Machine Learning (ICML), 2021
Annual Review of Neuroscience, 43:249-275, 2020
Conference on Learning Theory (CoLT), 2020
International Conference on Machine Learning, 2020
Frontiers in Neuroscience, 2019
Scientific Reports, 2019
Current Opinion in Neurobiology, 2019
Proceedings of the National Academy of Sciences, 116(30):15210-15215, 2019
Nature Neuroscience, 21(4):607-616, 2018
Journal of Open Source Software, 3(31):1003, 2018
Current Opinion in Neurobiology, 37:53-58, 2016
eLife, 4:e10015, 2015
Nature, 512:423-426, 2014